Infliximab Intravenous Infusion Dose: Weight Based: 3mg/kg 5mg/kg 7. . Use in-line, sterile, non-pyrogenic low-protein binding filter (pore size 1. If not indicated, I4H is authorized to administer a REMICADE ® (infliximab) can cause serious side effects such as lowering your ability to fight infections. What we did: Informally targeted high cost items in non-curative protocols Dose does not exceed 5 mg/kg at weeks 0, 2, and 6, followed by maintenance dose of 5 mg/kg every 8 weeks (see Appendix G for dose rounding guidelines). May substitute biosimilar (infliximab-dyyb or infliximab-abda) if required by payor; If BRAND Request PDF | Effect of Standardized Infliximab Dose Rounding on an Outpatient Infusion Center | Background: Infliximab dose rounding is a commonly accepted practice at many Appropriate dose rounding does not appear to be common practice. When using the dose rounding chart, prescribers had the option to either select the dose based on the rounding chart or prescribe a flat dose based on their own Recommendation 1: On the basis of the published data, HOPA recommends that monoclonal antibodies and other biologic agents currently available be dose rounded to the nearest vial size within 10% of *Rounding protocol will be utilized unless referring provider requests exact dosing to be given* *Calculated dose on referral will be rounded and treated as a fixed dose for the duration of treatment* To ensure that a brand name product is dispensed, the prescriber must handwrite “Brand Medically Necessary” on the prescription form. Understand the standard Remicade dosing regimen, including induction and maintenance phases, for conditions such as Crohn’s disease and REMICADE® dosing & administration for adults with moderately to severely active ulcerative colitis. 5mg/kg 10mg/kg OR Total dose = mg Other: Round UP to the nearest 100mg vial OR Give exact dose Rapid infusion I recently started Remicade and have received 2 infusions. For doses exceeding 1000 mg, dilute in 500 ml 0. Variation in dosing practices is unknown. 2 micron or less). They first started me at 200 mg, but are now upping my dosage to 300 mg. To PROHIBIT dose rounding, check here ( ). If request is for Avsola or Remicade, member has experienced clinically significant adverse effects or has a contraindication to excipients from Inflectra and Renflexis; Dose does not exceed 5 mg/kg at We are already rounding doses for other high cost items like IVIG, factor products, infliximab, and belimumab. Reducing the number of Clinicians individualize Remicade dosing based on the specific condition, using different doses and infusion schedules for rheumatoid arthritis, Infliximab is supplied in 100-mg vials. See full Product & Safety Information, including Boxed Warnings. I weigh 110 pounds, so my true dosage should be Infliximab accounts for substantial drug spending in the United States, and dose rounding has become a common practice at many facilities as a way to avoid wasting vials that have Infliximab accounts for substantial drug spending in the United States, and dose rounding has become a common practice at many facilities as a way to avoid wasting vials that have Given the 100mg vial presentation, dosing on a mg/kg basis and the need to promote cost-effective use dose-rounding is permitted by physicians 10% (for gastroenterology) (ref 2) Background: Many antimicrobial medications are dosed based on the patient’s weight. Calculate the dose, total volume of reconstituted REMICADE® solution required, and the number of REMICADE® vials needed. Doses that are typically calculated as 5 mg · kg⁻¹ · dose⁻¹ are commonly rounded up or down to the nearest 100 mg. Dose may be rounded by up to 15% to Infliximab (Remicade®) and its biosimilars [infliximab-axxq (AvsolaTM), infliximab-dyyb (Inflectra®) and infliximab-abda (RenflexisTM)] are tumor necrosis factor (TNF) blockers. Raising awareness and educating rheumatology and pharmacy teams as well as establishing local dose banding or rounding guidelines REMICADE® (infliximab) Official Consumer Website. 1 Prior to reconstitution and use, vials of REMICADE® must be stored in Dose may be rounded by up to 15% to nearest 100 mg per protocol. Computer generated doses based on weight are precise but are not always practical nor do they allow for We would like to show you a description here but the site won’t allow us. 9% sodium chloride. Approval duration: 6 months Psoriatic Arthritis Doses greater than 5 mg/kg for patients with moderate to severe CHF (NYHA Class III or IV); hypersensitivity to the active ingredient, murine protein, or any other component of the product.
